Orexin A Interactions in the Hypothalamo-Pituitary Gonadal Axis
نویسندگان
چکیده
منابع مشابه
Orexin A interactions in the hypothalamo-pituitary gonadal axis.
The distribution of orexin A-immunoreactive neurons and orexin type I receptors in the CNS suggests important roles in regulating the hypothalamo-pituitary gonadal (HPG) axis and sexual behaviors. We examined orexin A interactions in the HPG axis in vivo and in vitro. Orexin A stimulated LH-releasing hormone (LHRH) release in hypothalamic explants harvested from male rats (+133%) and from femal...
متن کاملThe hypothalamo-pituitary–gonadal axis
This review provides an outline of how our understanding of the neuroendocrine control of the hypothalamo-pituitary–gonadal axis has evolved since the publication of Geoffrey Harris’ renowned monograph in 1955. Particular attention is directed to the neurobiology underlying pulsatile GnRH release from the hypothalamus, the neuroendocrine control of ovarian cycles, puberty and seasonality of gon...
متن کاملSeasonal changes in the hypothalamo-pituitary-gonadal axis in birds.
Seasonal reproduction in birds is the adaptation to breed at the time of the greatest survival of young. This exact moment is mainly imposed by the photoperiod which stimulates the hypothalamo-pituitary-gonadal axis and starts breeding season. This article summarizes present knowledge concerning: 1/ perception and transduction of light into the biological signal; 2/ model of the avian photoperi...
متن کاملTachykinins and the hypothalamo-pituitary-gonadal axis: An update.
Tachykinins play a critical role in neuroendocrine regulation of reproduction. The best known members of the family are substance P (SP), neurokinin A and neurokinin B. Tachykinins mediate their biological actions through three G protein-coupled receptors, named NK1, NK2, and NK3. SP was suggested to play an important role in the ovulatory process in mammals and humans. Recent findings suggest ...
متن کاملHypothalamo-pituitary-gonadal axis in control of female reproductive cycle.
Gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus is pivotal to the regulation of reproductive physiology in vertebrates. The characteristic periodic secretion of gonadotropin releasing hormone (GnRH) from the medial basal hypothalamus (MBH), at the rate of one pulse an hour is essential for the maintenance of the menstrual cycle. These pulses are due to oscillations in the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinology
سال: 2001
ISSN: 0013-7227,1945-7170
DOI: 10.1210/endo.142.12.8558